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1

Pregnant women's perception of cesarean section on demand

Tschudin, Sibil, Alder, Judith, Hendriksen, Stephanie, Bitzer, Johannes, Popp, Karoline Aebi, Zanetti, Rosanna, Hösli, Irene, Holzgreve, Wolfgang, Geissbühler, Verena

Journal:

Journal of Perinatal Medicine

Year:

2009

Language:

english

File:

PDF, 98 KB

english, 2009

2

Structure-Based Design, Synthesis, and in vitro Evaluation of Nonpeptidic Neprilysin Inhibitors

Stefan Sahli, Bernhard Stump, Tobias Welti, Denise Blum-Kaelin, Johannes D. Aebi, Christian Oefner, Hans-Joachim Böhm, François Diederich

Journal:

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

3

α-Alkylation of Amino Acids without Racemization. Preparation of Either (S)- or (R)-α-Methyldopa from (S)-Alanine

Dieter Seebach, Johannes D. Aebi, Reto Naef, Theodor Weber

Journal:

Helvetica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 659 KB

english, 1985

4

Enantioselektive α-Alkylierung von Asparagin- und Glutaminsäure über die Dilithium-enolatocarboxylate von 2-[3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl]essigsäure und 3-[3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl]propionsäure

Johannes D. Aebi, Dieter Seebach

Journal:

Helvetica Chimica Acta

Year:

1985

File:

PDF, 908 KB

1985

5

Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

Dieter Seebach, Johannes D. Aebi, Marlyse Gander-Coquoz, Reto Naef

Journal:

Helvetica Chimica Acta

Year:

1987

File:

PDF, 1.65 MB

1987

6

Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-Ray Crystal-Structure Analysis

Stefan Sahli, Brian Frank, W. Bernd Schweizer, François Diederich, Denise Blum-Kaelin, Johannes D. Aebi, Hans-Joachim Böhm, Christian Oefner, Glenn E. Dale

Journal:

Helvetica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 472 KB

english, 2005

7

A New Class of Inhibitors for the Metalloprotease Neprilysin Based on a Central Imidazole Scaffold

Stefan Sahli, Bernhard Stump, Tobias Welti, W. Bernd Schweizer, François Diederich, Denise Blum-Kaelin, Johannes D. Aebi, Hans-Joachim Böhm

Journal:

Helvetica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 436 KB

english, 2005

8

Enantiomerenreine Synthesebausteine aus verzweigter Äpfelsäure

Johannes D. Aebi, Marius A. Sutter, Daniel Wasmuth, Dieter Seebach

Journal:

European Journal of Organic Chemistry

Year:

1983

File:

PDF, 804 KB

1983

9

Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: A model for the development of novel antiparasitic agents

Gianni Balliano, Henrietta Dehmlow, Simonetta Oliaro-Bosso, Matilde Scaldaferri, Silvia Taramino, Franca Viola, Giulia Caron, Johannes Aebi, Jean Ackermann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 228 KB

english, 2009

10

α-Alkylation of threonine

Dieter Seebach, Johannes D. Aebi

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 208 KB

english, 1983

11

α-alkylation of serine with self-reproduction of the center of chirality

Dieter Seebach, Johannes D. Aebi

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 222 KB

english, 1984

12

Synthesis of triazole-Tethered pyrrolidine libraries: novel ECE inhibitors

Eric A Kitas, Bernd-Michael Löffler, Stefan Daetwyler, Henrietta Dehmlow, Johannes D Aebi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 106 KB

english, 2002

13

Failure to visualise renal artery stenosis secondary to neurofibromatosis 1 by Doppler ultrasound

Christoph Aebi, Johannes M. Penzien, Heinz Tschäppeler, Mario G. Bianchetti

Journal:

Pediatric Nephrology

Year:

1993

Language:

english

File:

PDF, 124 KB

english, 1993

14

A fluorine scan of non-peptidic inhibitors of neprilysin: Fluorophobic and fluorophilic regions in an enzyme active site

Martin Morgenthaler, Johannes D. Aebi, Fiona Grüninger, Daniel Mona, Björn Wagner, Manfred Kansy, François Diederich

Journal:

Journal of Fluorine Chemistry

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

15

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Thoma, Ralf, Schulz-Gasch, Tanja, D'Arcy, Brigitte, Benz, Jörg, Aebi, Johannes, Dehmlow, Henrietta, Hennig, Michael, Stihle, Martine, Ruf, Armin

Journal:

Year:

2004

Language:

english

File:

PDF, 365 KB

english, 2004

16

Cytotoxic Effects of Combination of Oxidosqualene Cyclase Inhibitors with Atorvastatin in Human Cancer Cells

Staedler, Davide, Chapuis-Bernasconi, Catherine, Dehmlow, Henrietta, Fischer, Holger, Juillerat-Jeanneret, Lucienne, Aebi, Johannes D.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.99 MB

english, 2012

17

Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene−Hopene Cyclase

Lenhart, Alexander, Reinert, Dirk J., Aebi, Johannes D., Dehmlow, Henrietta, Morand, Oliver H., Schulz, Georg E.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 718 KB

english, 2003

18

Flow synthesis of annulated 5-aryl-substituted pyridines by tandem intramolecular inverse-electron-demand hetero-/retro-Diels–Alder reaction

Martin, Rainer E., Lenz, Mario, Alzieu, Thibaut, Aebi, Johannes D., Forzy, Liliane

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 836 KB

english, 2013

19

Synthesis and Structure−Activity Studies of Novel Orally Active Non-Terpenoic 2,3-Oxidosqualene Cyclase Inhibitors

Dehmlow, Henrietta, Aebi, Johannes D., Jolidon, Synèse, Ji, Yu-Hua, von der Mark, Elisabeth M., Himber, Jacques, Morand, Olivier H.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

20

Endothelin-Converting Enzyme-1 Inhibition and Growth of Human Glioblastoma Cells

Berger, Yann, Dehmlow, Henrietta, Blum-Kaelin, Denise, Kitas, Eric A., Löffler, Bernd-Michael, Aebi, Johannes D., Juillerat-Jeanneret, Lucienne

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 432 KB

english, 2005

21

Synthesis, conformation, and immunosuppressive activities of three analogs of cyclosporin A modified in the 1-position

Aebi, Johannes D., Deyo, Donald T., Sun, Chong Qing, Guillaume, Dominique, Dunlap, Brian, Rich, Daniel H.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.68 MB

english, 1990

22

Synthesis, conformation and immunosuppressive activity of a conformationally restricted cyclosporin lactam analog

Aebi, Johannes D., Guillaume, Dominique, Dunlap, Brian E., Rich, Daniel H.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.41 MB

english, 1988

23

A short synthesis of enantiomerically pure (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoic acid, the unusual C9 amino acid found in the immunosuppressive peptide cyclosporine

Aebi, Johannes D., Dhaon, Madhup K., Rich, Daniel H.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 909 KB

english, 1987

24

Previous birth experience and birth anxiety: predictors of caesarean section on demand?

Tschudin, Sibil, Alder, Judith, Hendriksen, Stephanie, Bitzer, Johannes, Popp, Karoline Aebi, Zanetti, Rosanna, Hösli, Irene, Holzgreve, Wolfgang, Geissbühler, Verena

Journal:

Journal of Psychosomatic Obstetrics & Gynecology

Year:

2009

Language:

english

File:

PDF, 262 KB

english, 2009

25

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys

Martin, Rainer E., Aebi, Johannes D., Hornsperger, Benoit, Krebs, Hans-Jakob, Kuhn, Bernd, Kuglstatter, Andreas, Alker, André M., Märki, Hans Peter, Müller, Stephan, Burger, Dominique, Ottaviani, Gior

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.80 MB

english, 2015

26

Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2)

Martin, Rainer E., Lehmann, Johannes, Alzieu, Thibaut, Lenz, Mario, Carnero Corrales, Marjorie A., Aebi, Johannes D., Märki, Hans Peter, Kuhn, Bernd, Amrein, Kurt, Mayweg, Alexander V., Britton, Rober

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 639 KB

english, 2016

27

Oxidosqualene Cyclase (OSC) Inhibitors for the Treatment of Dyslipidemia

Dehmlow, Henrietta, Ackermann, Jean, Aebi, Johannes, Blum-Kaelin, Denise, Chucholowski, Alexander, Coassolo, Philippe, Hartman, Peter, Kansy, Manfred, Märki, Hans Peter, Morand, Olivier, Von Der Mark,

Journal:

CHIMIA International Journal for Chemistry

Year:

2005

Language:

english

File:

PDF, 645 KB

english, 2005

28

Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors

Qiu, Zongxing, Kuhn, Bernd, Aebi, Johannes, Lin, Xianfeng, Ding, Haiyuan, Zhou, Zheng, Xu, Zhiheng, Xu, Danqing, Han, Li, Liu, Cheng, Qiu, Hongxia, Zhang, Yuxia, Haap, Wolfgang, Riemer, Claus, Stahl,

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

29

ChemInform Abstract: Flow Synthesis of Annulated 5-Aryl-Substituted Pyridines by Tandem Intramolecular Inverse-Electron-Demand hetero/retro-Diels-Alder Reaction.

Martin, Rainer E., Lenz, Mario, Alzieu, Thibaut, Aebi, Johannes D., Forzy, Liliane

Journal:

Year:

2014

File:

PDF, 34 KB

2014

30

Targeted gamma-secretase inhibition of Notch signaling activation in acute renal injury

Wyss, Jean-Christophe, Kumar, Rajesh, Mikulic, Josip, Schneider, Manfred, Aebi, Johannes D, Juillerat-Jeanneret, Lucienne, Golshayan, Dela

Journal:

American journal of physiology. Renal physiology

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

31

Ligand channel in pharmacologically stabilized rhodopsin

Mattle, Daniel, Kuhn, Bernd, Aebi, Johannes, Bedoucha, Marc, Kekilli, Demet, Grozinger, Nathalie, Alker, Andre, Rudolph, Markus G., Schmid, Georg, Schertler, Gebhard F. X., Hennig, Michael, Standfuss,

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

32

Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells

Hyder, Salman, Liang, Yayun, Mafuvadze, Benford, Aebi, Johannes

Journal:

OncoTargets and Therapy

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

33

Differential Effects of the Mitochondria-Active Tetrapeptide SS-31 (D-Arg-dimethylTyr-Lys-Phe-NH2) and Its Peptidase-Targeted Prodrugs in Experimental Acute Kidney Injury

Wyss, Jean-Christophe, Kumar, Rajesh, Mikulic, Josip, Schneider, Manfred, Mary, Jean-Luc, Aebi, Johannes D., Juillerat-Jeanneret, Lucienne, Golshayan, Dela

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 2.35 MB

english, 2019

34

Differential Effects of the Mitochondria-Active Tetrapeptide SS-31 (D-Arg-dimethylTyr-Lys-Phe-NH2) and Its Peptidase-Targeted Prodrugs in Experimental Acute Kidney Injury

Wyss, Jean-Christophe, Kumar, Rajesh, Mikulic, Josip, Schneider, Manfred, Mary, Jean-Luc, Aebi, Johannes D., Juillerat-Jeanneret, Lucienne, Golshayan, Dela

Journal:

Frontiers in Pharmacology

Year:

2019

File:

PDF, 2.35 MB

2019

35

Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors

Liu, Yongfu, Wu, Jun, Zhou, Mingwei, Chen, Wenming, Li, Dongbo, Wang, Zhan-Guo, Hornsperger, Benoit, Aebi, Johannes D., MÃ¤rki, Hans-Peter, Kuhn, Bernd, Wang, Lisha, Kuglstatter, Andreas, Benz, JÃ¶rg,

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.11 MB

2020

36

Architecture and function of human uromodulin filaments in urinary tract infections

Weiss, Gregor L., Stanisich, Jessica J., Sauer, Maximilian M., Lin, Chia-Wei, Eras, Jonathan, Zyla, Dawid S., TrÃ¼ck, Johannes, Devuyst, Olivier, Aebi, Markus, Pilhofer, Martin, Glockshuber, Rudi

Journal:

Year:

2020

File:

PDF, 1.98 MB

2020